An experimental diet pill weight loss helped about half of those who took it, but it recovered a year later and no heart problems caused by other drugs, a study found.
Lorcaserin, Arena Pharmaceuticals, is one of three drugs that are raising hopes that a new generation of more effective pills to lose weight. One of them will be reviewed on Thursday the Food and Drug Administration (FDA, for its acronym in English), and the others they will be later this year.
In the study, lorcaserin caused more people to lose at least 5% of their body weight in a year, more than double that achieved by those taking a placebo.
Most people do not stick to diets and diet pills have side effects or can not be taken for long periods. A critical point came in 1997 when the popular "fen-phen was recalled after being linked to heart valve problems.
But now comes lorcaserin, tablet round blue pill would be the first truly new weight loss in ten years to obtain approval. The drug targets the same path appetite did the fen-phen, but in a more selective and perhaps safer.
The results of a large study funded by the drug company appear on Thursday in the journal New England Journal of Medicine.
The investigation involves more than 3,100 obese or overweight people who took the pill or a placebo.
After a year, nearly 48% of lorcaserin group had a loss of at least 5% of their body weight, on average approximately 5.8 kilograms (13 pounds). Only 20% of the group taking a placebo lost that weight.
Only half the study participants completed the years. This is not unusual, typically many drop out of studies on diet. But there were fewer desertions lorcaserin group than in the placebo, suggesting that side effects were not a problem.
Except for headache and dizziness, essentially no side effects were worse with the drug compared with placebo. There was a higher rate of heart valve problems, which was a critical concern. However, further studies are needed to conclusively rule out this risk.
Arena, located in San Diego, has not put a price to lorcaserin. But it could be especially useful for obese patients with heart failure.
The other two drugs to be evaluated by the FDA are combinations of drugs already on the market.
viernes, 16 de julio de 2010
miércoles, 30 de junio de 2010
English woman's age is removed in order to win beauty contest
Laura Annes, a 27 year old woman wanted since childhood to become queen of beauty. In order to achieve in 2006 was entered in the contest of Cornwall, England, without a win. However, his ambition to be 'Miss' led her to be in the years 2007, 2008 and 2010 in the latter getting the scepter and crown.
But contest organizers realized that the previous records in the old box, Annes put 22 years in all. Therefore, the calculations do well and having spent four years since the first time that appeared the woman had already served 27.
However, this was not his only lie. Laura indicated that lived in Saltash, Cornwall but his real home is in Plymouth, Devon.
After learning of this situation, not only Annes had to apologize publicly but they also longed to return your crown.
But contest organizers realized that the previous records in the old box, Annes put 22 years in all. Therefore, the calculations do well and having spent four years since the first time that appeared the woman had already served 27.
However, this was not his only lie. Laura indicated that lived in Saltash, Cornwall but his real home is in Plymouth, Devon.
After learning of this situation, not only Annes had to apologize publicly but they also longed to return your crown.
Three easy to follow tips to lower the extra kilos
You've put on a diet but do not see the results clearly. You may have downloaded a couple of kilos but feel the need to go lower. If this is your case, we bring you three steps that will help you lose those extra inches you want to counter.
Taking a week
"Lots of training? Do you spend hours in the gym and do not lose an ounce or more? Perhaps it is because your body is scared and retain water, or simply reserves. Your own body is concerned that you leave with nothing. Give him a break and loose or give up your training plan for a week, trying to maintain the diet.
Increase your intake of protein
More protein in your diet? Yes, lose more weight and eat fewer calories, more protein you need. They will help you not lose muscle mass and improve metabolism. The best sources of protein are chicken, egg whites and fish.
Combine workouts
Cardio exercises do not have to destroy your body begging for mercy. Note that you can (and should) change the method you're using and start with 6-8 cardio session intervals of 30 seconds sprints interspersed with 90 seconds rest. And then closes the session with 15 minutes of cardio calm. Combine workouts will give you the necessary metabolic key.
Taking a week
"Lots of training? Do you spend hours in the gym and do not lose an ounce or more? Perhaps it is because your body is scared and retain water, or simply reserves. Your own body is concerned that you leave with nothing. Give him a break and loose or give up your training plan for a week, trying to maintain the diet.
Increase your intake of protein
More protein in your diet? Yes, lose more weight and eat fewer calories, more protein you need. They will help you not lose muscle mass and improve metabolism. The best sources of protein are chicken, egg whites and fish.
Combine workouts
Cardio exercises do not have to destroy your body begging for mercy. Note that you can (and should) change the method you're using and start with 6-8 cardio session intervals of 30 seconds sprints interspersed with 90 seconds rest. And then closes the session with 15 minutes of cardio calm. Combine workouts will give you the necessary metabolic key.
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